Slc gene family
WebApr 19, 2024 · Identification of a Solute Carrier Family-Based Signature for Predicting Overall Survival in Osteosarcoma Identification of a Solute Carrier Family-Based Signature for Predicting Overall Survival in Osteosarcoma Front Genet. 2024 Apr 19;13:849789. doi: 10.3389/fgene.2024.849789. eCollection 2024. Authors Di Zheng 1 , Zhun Wei 1 , Weichun … WebMar 1, 2012 · The SoLute Carrier (SLC) Family Series in Teleost Fish. In: Functional Genomics in Aquaculture March 2012 In book: Functional Genomics in Aquaculture (pp.219-320) Publisher:...
Slc gene family
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WebThe SLC8 gene family of sodium-calcium exchangers (NCX) - Structure, function, and regulation in health and disease. Mol Aspects Med. 2013 Apr;34(2-3):220-35. SLC name The solute carrier (SLC) group of membrane transport proteins include over 400 members organized into 66 families. Most members of the SLC group are located in the cell membrane. The SLC gene nomenclature system was originally proposed by the HUGO Gene Nomenclature Committee (HGNC) and is the … See more By convention of the nomenclature system, members within an individual SLC family have greater than 20-25% sequence identity to each other. In contrast, the homology between SLC families is very low to non-existent. … See more The following families are named under SLC: 1. high-affinity glutamate and neutral amino acid transporter See more Putative SLCs, also called atypical SLCs, are novel, plausible secondary active or facilitative transporter proteins that share ancestral background with the known SLCs. The atypical … See more Most members of the SLC group are located in the cell membrane, but some members are located in mitochondria (the most notable one being SLC family 25) or other intracellular organelles. See more Names of individual SLC members have the following format: where: • SLC is the root name (SoLute Carrier) • n = an integer representing a family (e.g., 1-52) • X = a single letter (A, B, C, ...) denoting a subfamily See more • Outline of families • Datasets and Reagents on the Solute Carrier Family • List of proteins at HGNC website See more
WebNormal Function. The SLC25A24 gene provides instructions for producing a protein that is a member of the solute carrier (SLC) family of proteins. Proteins in the SLC family transport … WebJan 15, 2024 · Solute carrier (SLC) family 39 genes encode membrane transport proteins, which control the influx of zinc and may play important roles in human disease including cancer. However, the prognostic value of individual SLC family 39 gene in gastric cancer patients remain unclear.
WebApr 1, 2009 · Many of these transporters belong to the solute-carrier (SLC) gene superfamily, and include passive transporters, sym-porters and antiporters, as well as mitochondrial and vesicular transporters. The SLC superfamily comprises 55 gene families, having at least 362 putatively functional protein-coding genes . WebApr 30, 2024 · The SLC16A family of monocarboxylate transporters (MCTs) is a subfamily of solute carriers that transport monocarboxylate molecules, including L-lactate and pyruvate, across cell membranes 3....
WebSep 20, 2024 · Association of clinical severity of cystic fibrosis with variants in the SLC gene family (SLC6A14, SLC26A9, SLC11A1 and SLC9A3) Author links open overlay panel Stéphanie Villa-Nova Pereira a, José Dirceu Ribeiro b c, Carmen Sílvia Bertuzzo a, Fernando Augusto Lima Marson a b c. Show more.
WebFeb 1, 2009 · The solute carrier (Slc) superfamily is a major group of membrane transport proteins present in mammalian cells. Although Slc transporters play essential and diverse roles in the central... shepard caseWebThe overview of human SLC superfamily. The human SLC superfamily comprises 386 member proteins that transport a broad spectrum of substrates, such as nutrients, toxins, … spray proof toilet lidWebDec 4, 2024 · There are ~ 430 known transporters in the solute-linked carrier (SLC) gene family, divided into 52 distinct families. Eleven of these gene families contain one or more amino acid transporters. These transporters differ significantly from each other in terms of substrate specificity, ion dependence, and energetics. spray protector for grass rugsWebNov 18, 2003 · The SLC series includes genes encoding passive transporters, ion compled transporters and exchangers (see Fig. 1 ). A transporter has been assigned to a specific SLC family if it has at least 20–25% amino acid sequence identity to … spray pump for cosmeticsWebThe SLC superfamily currently includes 458 transport proteins in 65 families that carry a wide variety of substances across cellular membranes. While members of this superfamily are found throughout cellular organelles, this review focuses on transporters expressed at the plasma membrane. spray protein for hairWebDec 15, 2024 · To construct an SLC family gene signature, we first divided the TCGA LUAD cohort (entire cohort) into a training cohort and a testing cohort at a ratio of … spray property for ticksWebThe SLC (Solute Carrier) series includes the “classical” transporter families (ion-coupled transporters, exchangers, passive transporters, etc.). It contains 65 SLC gene families with 458 different human transporter … spray pu foam insulation