Pdz and lim domain 5
Splet06. jan. 2024 · As a part of the Enigma family, LDB3 contains the N-terminal PDZ domain and three LIM domains at the C-terminus 4,5. The association of the PDZ and LIM modular protein-interacting domains allows ... SpletPDZ Domain. PDZ domains are well-defined structural motifs of around 80–90 amino acids organized in six β-sheets (βA–βF) and two α-helices (αA, αB).46,47 PDZ …
Pdz and lim domain 5
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Splet04. dec. 2024 · PDLIM5 is involved in psychiatric disorders, including mood disorders ENH1 with multiple protein-protein interaction modules is essential for differentiation of striated … SpletA gene on chromosome 4q22 that encodes a LIM-domain protein that has cysteine-rich double-zinc fingers involved in protein-protein interactions; it is also an enigma protein containing a PDZ domain, which are found in signalling proteins. PDLIM5 is thought to play a role in heart development as an integral component of heart cell scaffolding.
SpletPDZ domains are protein-interaction domains that are often found in multi-domain scaffolding proteins. PDZ-containing scaffolds assemble specific proteins into large molecular complexes at defined locations in the cell. SpletPDZ and LIM domain protein 5 is a protein that in humans is encoded by the PDLIM5 gene. The protein encoded by this gene is a LIM domain protein. LIM domains are cysteine-rich …
SpletWe identified PDZ and LIM domain 5 (PDLIM5) as a novel target of miR-17∼92 in human PASMC (HPASMC) and showed that miR-17∼92 regulates SMC phenotype via the PDLIM5/transforming growth factor (TGF)-β 3 /Smad3 pathway. Loss of SMC-specific PDLIM5 enhanced hypoxia-induced PH in mice, whereas overexpression of PDLIM5 … Splet21. mar. 2024 · PDLIM5 (PDZ And LIM Domain 5) is a Protein Coding gene. Diseases associated with PDLIM5 include Nail-Patella Syndrome and Bipolar Disorder . Among its …
Splet02. nov. 2006 · The deduced proteins contain 366, 352, and 278 amino acids and have calculated molecular masses of 39.2, 37.5, and 29.1 kD, respectively. Mystique-1 and -2 have an N-terminal PDZ domain and a C-terminal LIM domain separated by about 200 amino acids, but they differ at their C termini. Mystique-3 has only the PDZ domain due to …
Splet29. mar. 2024 · PDLIM5 PDZ and LIM domain 5 [ (human)] Gene ID: 10611, updated on 5-Mar-2024 Summary This gene encodes a member of a family of proteins that possess a … tiger shark companySplet10. apr. 2024 · Bauer, K. et al. Human CLP36, a PDZ-domain and LIM-domain protein, binds to alpha-actinin-1 and associates with actin filaments and stress fibers in activated platelets and endothelial cells. theme ou termeSplet05. nov. 2001 · Cypher is a member of a recently emerging family of proteins containing a PDZ domain at their NH 2 terminus and one or three LIM domains at their COOH terminus. Cypher knockout mice display a severe form of congenital myopathy and die postnatally from functional failure in multiple striated muscles. Examination of striated muscle from … theme outfit generatorSpletSH3结构域 (英語: SH3 domain ,全称 Src同源3结构域 ,英語: SRC Homology 3 Domain )是最早在 病毒 接头蛋白 v-Crk及 酪氨酸激酶 Src 、 Abl 中发现的长约60个 氨基酸 残基的 保守 结构域 [1] [2] ,在 磷酸肌醇3-激酶 、 Ras超家族 G蛋白 、 cdc25 中也存在 … theme osrsSplet05. mar. 2015 · PDZ and LIM domain protein 1 (PDLIM1)/CLP36 promotes breast cancer cell migration, invasion and metastasis through interaction with α-actinin PDZ and LIM domain protein 1 (PDLIM1)/CLP36 promotes breast cancer cell migration, invasion and metastasis through interaction with α-actinin Oncogene. 2015 Mar 5;34 (10):1300-11. doi: … theme outfits ideasSplet专利汇可以提供PDLIM3(PDZ and LIM domain 3)用作胃癌标志物的应用专利检索,专利查询,专利分析的服务。并且本 发明 公开了PDLIM3作为胃癌诊断标志物的应用。本发明研究发现,胃癌患者PDLIM3基因或蛋白的表达 水 平与健康人或者癌旁组织相比,表达水平显著升高,因此可作为胃癌诊断标志物,用于制备 ... tiger shark caught in south padre islandSplet专利汇可以提供PDLIM3(PDZ and LIM domain 3)用作胃癌标志物的应用专利检索,专利查询,专利分析的服务。并且本 发明 公开了PDLIM3作为胃癌诊断标志物的应用。本发明研 … theme outfits for work