N n-dimethylaniline monooxygenase activity

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August undefined, 2024

WebN,N-dimethylaniline monooxygenase activity trimethylamine monooxygenase activity Process metabolic process oxidation reduction Cellular Location Endoplasmic reticulum membrane Microsome membrane Gene Properties Chromosome Location 1 Locus 1q24.3 SNPs FMO3 Gene Sequence >1599 bp … WebApr 15, 2024 · Epoxide hydrolases are attractive and industrially important biocatalysts. They can catalyze the enantioselective hydrolysis of epoxides to the corresponding diols as chiral building blocks for bioactive compounds and drugs. In this review article, we discuss the state of the art and development potential of epoxide hydrolases as biocatalysts …

856581 - Gene ResultFMO1 N,N-dimethylaniline monooxygenase []

WebAcute inhalation exposure to N,N-dimethylaniline has resulted in effects on the CNS and circulatory system, with headache, cyanosis, dizziness, labored breathing, paralysis, and … Webflavin containing dimethylaniline monoxygenase 3: RGD ID: 619761: Description: Enables N,N-dimethylaniline monooxygenase activity; NADP binding activity; and amino acid binding activity. Involved in xenobiotic metabolic process. Located in intracellular membrane-bounded organelle. grey headboard king size bed

Dimethylaniline monooxygenase [N-oxide-forming] 1 - DrugBank

WebN,N-Dimethylaniline is an organic compound. It is a colorless to pale yellow liquid with a pungent odor at room temperature and pressure. N,N-Dimethylaniline is widely used in the chemical industry for dyes, pharmaceuticals, pesticides, rubber, plastics, and as an intermediate and reagent for reactions. It can also be used as a catalyst and ... WebThe flavin-containing monooxygenases are NADPH-dependent enzymes that catalyze the oxidation of many drugs and xenobiotics. In most mammals, there is a flavin-containing monooxygenase that catalyzes the N-oxidation of some primary alkylamines through an N-hydroxylamine intermediate. WebN,N-Dimethylaniline (DMA) Intermediates. ding 2024-04-13T17:29:06+08:00. N,N-Dimethylaniline is an organic compound. It is a colorless to light yellow oily liquid with a pungent odor at room temperature and pressure. grey headboard with white bedding

Flavin-containing monooxygenase 3 - Wikipedia

FMO2 - Dimethylaniline monooxygenase [N-oxide-forming] 2

WebJan 14, 2013 · It N-oxygenates primary aliphatic alkylamines as well as secondary and tertiary amines. Plays an important role in the metabolism of trimethylamine (TMA), via the production of TMA N-oxide (TMAO). Is also able to perform S-oxidation when acting on sulfide compounds (PubMed:9224773). Pfam Domain Function FMO-like ( PF00743) … WebN,N-dimethylaniline monooxygenase; localizes to ER membrane and cytosol View computational annotations Molecular Function Manually Curated enables N,N-dimethylaniline monooxygenase activity ( IDA ) Biological Process Manually Curated involved in protein folding ( IDA ) Cellular Component Manually Curated grey headboard fullFlavin-containing monooxygenase 3 (FMO3), also known as dimethylaniline monooxygenase [N-oxide-forming] 3 and trimethylamine monooxygenase, is a flavoprotein enzyme (EC 1.14.13.148) that in humans is encoded by the FMO3 gene. This enzyme catalyzes the following chemical reaction, among others: trimethylamine + NADPH + H + O2 trimethylamine N-oxide + NADP + H2O fidelity roth basic 401k

"WebID FMO5_MOUSE Reviewed; 533 AA. AC P97872; Q8R1W6; DT 15-JUL-1998, integrated into UniProtKB/Swiss-Prot. DT 27-JUL-2011, sequence version 4. " - N n-dimethylaniline monooxygenase activity

N n-dimethylaniline monooxygenase activity

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WebMetabolic N-oxidation of the diet-derived amino-trimethylamine (TMA) is mediated by flavin-containing monooxygenase and is subject to an inherited FMO3 polymorphism in man resulting in a small subpopulation with reduced TMA N-oxidation capacity resulting in fish odor syndrome Trimethylaminuria. WebJan 14, 2013 · 1.14.13.8. H (+) + N,N-dimethylaniline + NADPH + O2 <=> H2O + N,N-dimethylaniline N-oxide + NADP (+) A broad spectrum monooxygenase that accepts substrates as diverse as hydrazines, phosphines, boron-containing compounds, sulfides, selenides, iodide, as well as primary, secondary and tertiary amines. Is distinct from other …

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WebIt is probable that this protein is only produced in very small quantity or not at all as the gene coding for it seems to be unable to produce full-length transcripts. Caution Could be the … WebN,N-dimethylaniline monooxygenase activity Gene Ontology Term (GO:0004499) Home Genes Human Disease Expression Recombinases Function Strains / SNPs Homology …

WebNov 4, 2024 · Title: The Arabidopsis flavin-dependent monooxygenase FMO1 is an essential component of biologically induced systemic acquired resistance. FMO1 and NUDT7 are … http://ic4r.org/genes/IC4R-OSJ01G108100

WebLiver microsomal benzydamine N-oxygenation was inhibited by dimethyl sulfoxide and methimazole, whereas N-demethylation was inhibited by quinidine. High benzydamine N-oxygenation activities of recombinant human FMO1 and FMO3 and human kidney microsomes were observed at pH 8.4, whereas N-demethylation by cytochrome P450 2D6 … WebFeb 15, 2024 · Flavin monooxygenase-like Catalytic Activity (EC) Experimental Evidence - Predictions / Assertions H (+) + N,N-dimethylaniline + NADPH + O2 = H2O + N,N-dimethylaniline N-oxide + NADP (+) ( 1.14.13.8 ) Summaries Gene Model and Products Expression Data Alleles, Insertions, Transgenic Constructs, and Aberrations Variants …

WebTarget Alias Description ECC score Gene Family Method Actions; Bradi1g12440: No alias: Major facilitator superfamily protein: 0.03: OrthoFinder 130319: Glyma.11G106300

grey headboard room decorWebIn vitro, catalyzes the N-oxygenation of trimethylamine (TMA) to produce trimethylamine N-oxide (TMAO) and could therefore participate to the detoxification of this compound that is generated by the action of gut microbiota from dietary precursors such as choline, choline containing compounds, betaine or L-carnitine ( By similarity ). By similarity fidelity roth conversion in kindWebGO:0004499 N,N-dimethylaniline monooxygenase activity; Reaction participants Show >> << Hide. ... enhanced the MPTP N-oxygenation activity by 51%, while methimazole, thiobenzamide and alpha-naphthylthiourea, alternate substrates of FMO, inhibited it by 27.4, 68.0 and 59.2%, respectively. The results indicate that MPTP is efficiently N ... fidelity roth 401k plansWebN -oxide and S -oxide formation represent the major FMO-mediated reactions In contrast to most CYP isoenzymes, the FMOs bind and activate molecular oxygen before the substrate … grey headboard super king sizeWebMetalloporphyrin catalyzed oxidation of methyl yellow and related azo compounds grey head cone flowerWebPredicted to enable N,N-dimethylaniline monooxygenase activity and aldehyde oxidase activity. Involved in regulation of cholesterol metabolic process. Predicted to be located in … grey-headedWebPredicted to enable N,N-dimethylaniline monooxygenase activity and aldehyde oxidase activity. Involved in regulation of cholesterol metabolic process. Predicted to be located in cytosol and endoplasmic reticulum. Is expressed in bladder. Orthologous to human FMO5 (flavin containing dimethylaniline monoxygenase 5). [provided by Alliance of Genome … fidelity roth conversion ladder